Volume 6, Issue 1, June 2018, Page: 33-39
Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment
Hasyizan Mohamad Hassan, Department of Anesthesia and Intensive Care, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Nurul Ashikin Hasbullah, Department of Anesthesia and Intensive Care, Hospital Raja Perempuan Zainab 2, Kota Bharu, Malaysia
Saedah Ali, Department of Anesthesia and Intensive Care, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Ruwaida Isa, Department of Anesthesia and Intensive Care, Hospital Raja Perempuan Zainab 2, Kota Bharu, Malaysia
Received: Jan. 14, 2018;       Accepted: May 14, 2018;       Published: Jul. 4, 2018
DOI: 10.11648/j.ja.20180601.16      View  614      Downloads  31
Abstract
The ideal intraoperative intravenous fluid in paediatric anaesthesia and surgery is still debatable. This is essential to overcome physiological changes to maintain safety and wellbeing of the patient. A new isotonic “balanced solution” (Sterofundin ® ISO) has been introduced to replace existing intraoperative fluid of choice (Ringer’s Lactate). The study aimed to observe any changes in electrolytes and acid base after infusion of each study solutions and to evaluate any post infusion electrolytes and acid base differences between both study solutions. The double blinded randomized control trial involved 141 paediatric patients who were subjected to minor surgical procedure of less than 3 hours were randomized into Ringer’s Lactate or Sterofundin ® ISO group. The electrolytes and acid base parameters were assessed at pre-infusion and post-infusion time. There were significant difference in glucose, potassium (K+) and chloride (Cl-) level between pre-infusion and post-infusion values with those given Ringer’s Lactate. There were also significant different in pH, base excess, glucose, Calcium (Ca2+), Chloride (Cl) and lactate level between pre-infusion and post-infusion values with Sterofundin ® ISO. When comparing the mean difference (pre-infusion and post-infusion) between Ringer’s Lactate and Sterofundin ® ISO, calcium (Ca2+) is the only electrtolyte which found to be significant (P=0.015) with the values of (Means±SD 0.005±0.07) mmol/L and (Means±SD 0.02±0.06) mmol/L respectively. Both study solutions showed variable effects of electrolytes and acid base parameters and no fluid was found to be superior in paediatric surgical patients underwent minor surgery of less than three hours.
Keywords
Sterofundin ® ISO, Ringer’s Lactate, Paediatric, Minor Surgery, Electrolytes, Acid-Base Balance
To cite this article
Hasyizan Mohamad Hassan, Nurul Ashikin Hasbullah, Saedah Ali, Ruwaida Isa, Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment, Journal of Anesthesiology. Vol. 6, No. 1, 2018, pp. 33-39. doi: 10.11648/j.ja.20180601.16
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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